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Women's Health Supplements For Hormonal Balance, Fertility + Menopause

EVIDENCE BASED

Evidence Based

iHerb has strict sourcing guidelines and draws from peer-reviewed studies, academic research institutions, medical journals, and reputable media sites. This badge indicates that a list of studies, resources, and statistics can be found in the references section at the bottom of the page.

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The Importance Of Nutrition In Women's Health

Hormonal changes are a natural part of every woman’s life, from navigating PMS and fertility challenges to the transition into menopause. But when hormones fall out of balance, they can affect everything from mood and energy to sleep, skin, and even heart and bone health.

That’s where nutrition plays a powerful role. A balanced diet rich in colorful vegetables, fruits, whole grains, lean proteins, and healthy fats (like those found in the Mediterranean diet) helps reduce inflammation, which is a common root cause of hormonal imbalances. 

Foods high in omega-3s, antioxidants, and phytonutrients support hormone production, reduce discomfort, and promote long-term wellness.

On the flip side, highly processed foods, excess sugar, and trans fats can make symptoms worse by increasing inflammation and disrupting your body’s natural rhythms.

While food should always be the foundation, targeted supplements can provide a helpful boost, especially during times of hormonal transition, stress, or when dietary gaps are hard to fill. Whether you’re trying to support fertility, soothe menstrual symptoms, or ease into menopause with more grace, smart supplementation can make a real difference.

Supplements For Fertility

Fertility can be affected by many factors, including hormonal imbalances and inflammation. Fortunately, several supplements are backed by science to support reproductive health:

PCOS (Polycystic Ovary Syndrome)

  • Myo-inositol & D-chiro-inositol: These naturally occurring nutrients support hormone balance, insulin sensitivity, and ovulation. They are often used together to help women with PCOS improve their chances of conception. Look for supplements with a combined dose of up to 4 grams per day. Look for balanced formulas that combine both types of inositol, ideally with antioxidants and vitamins.
  • NAC (N-acetyl cysteine): A powerful antioxidant that supports liver health and reduces inflammation. It can improve ovulation and egg quality. A common dose is 600 mg taken three times daily.
  • Chromium: Helps the body regulate blood sugar and improve insulin function, which is especially helpful for women with PCOS. A typical dose is 200 mcg daily.

Other Key Fertility Nutrients

  • Coenzyme Q10: Supports mitochondrial health and egg quality, especially as women age. Doses range from 300 to 600 mg daily.
  • Antioxidants (Vitamins C, E, Selenium, Zinc): Help combat oxidative stress that can affect fertility. Look for a quality women’s multivitamin.
  • B Vitamins (especially Folate and B12): Essential for reproductive health, especially for women of childbearing age.
  • Vitamin D: Supports ovulation and hormone balance. Daily doses between 3200 and 7000 IU are often recommended.

Explore iHerb’s fertility support section for top-rated supplements in easy-to-take capsules, powders, or gummies.

Supplements For Hormonal Balance

Hormonal fluctuations during the menstrual cycle can cause a range of symptoms, such as cramps, mood swings, bloating, migraines, and more. These supplements can help you feel more balanced and in control:

  • Magnesium: Helps ease cramping, bloating, and irritability. Also supports mood and metabolism. Aim for 400–600 mg daily.
  • Calcium + Vitamin D: Together, they can reduce uterine muscle contractions and support bone health.
  • Ginger: A natural anti-inflammatory that may reduce menstrual pain.
  • Chaste Tree Berry (Vitex): Supports progesterone levels and reduces PMS symptoms like anxiety, bloating, and mood changes. Best results after three months of use.

Look for women’s hormonal health blends on iHerb featuring these key ingredients.

Supplements For Menopause

Menopause brings its own set of challenges due to declining estrogen levels. These challenges may include hot flashes, night sweats, brain fog, and increased risk of bone loss and heart disease. These supplements can ease the transition:

  • Probiotics (Lactobacillus strains): Help maintain vaginal and urinary health during menopause. Some strains, like Lactobacillus acidophilus YT1, have shown benefits for hot flashes, mood, and vaginal health.
  • Calcium + Vitamin D + Vitamin K2: This trio supports strong bones and reduces fracture risk in postmenopausal women.
  • Evening Primrose Oil: Rich in gamma-linolenic acid (GLA), this oil may help with hot flashes and skin hydration.
  • Phytoestrogens (Soy Isoflavones, Red Clover): Plant compounds that mimic estrogen in the body and may reduce hot flashes.
  • B Vitamins: B6 and B12 support energy, mood, and cardiovascular health. A multivitamin for women over 50 can help fill common nutrient gaps, especially B12, D3, and K2. Gummy multivitamins with B12 and biotin are a convenient option to support energy, metabolism, and hair health.

Find menopause support supplements on iHerb in capsules, oils, and plant-based formulas.

References:

  1. Kennard A, Gillespie E, McKendree R. Integrative Medicine in Women. Prim Care Clin Off Pract. Published online March 1, 2025. doi:10.1016/j.pop.2025.01.003
  2. Mohammadi MM, Mirjalili R, Faraji A. The impact of omega-3 polyunsaturated fatty acids on primary dysmenorrhea: a systematic review and meta-analysis of randomized controlled trials. Eur J Clin Pharmacol. 2022;78(5):721-731. doi:10.1007/s00228-021-03263-1
  3. Romm AJ. Botanical Medicine for Women’s Health. Elsevier; 2018.
  4. Teede HJ, Tay CT, Laven JJE, et al. Recommendations From the 2023 International Evidence-based Guideline for the Assessment and Management of Polycystic Ovary Syndrome. J Clin Endocrinol Metab. 2023;108(10):2447-2469. doi:10.1210/clinem/dgad463
  5. Greff D, Juhász AE, Váncsa S, et al. Inositol is an effective and safe treatment in polycystic ovary syndrome: a systematic review and meta-analysis of randomized controlled trials. Reprod Biol Endocrinol. 2023;21(1):10. Published 2023 Jan 26. doi:10.1186/s12958-023-01055-z
  6. Unfer V, Facchinetti F, Orrù B, Giordani B, Nestler J. Myo-inositol effects in women with PCOS: a meta-analysis of randomized controlled trials. Endocr Connect. 2017;6(8):647-658. doi:10.1530/EC-17-0243
  7. Alesi S, Ee C, Moran LJ, Rao V, Mousa A. Nutritional Supplements and Complementary Therapies in Polycystic Ovary Syndrome. Adv Nutr. 2021;13(4):1243-1266. doi:10.1093/advances/nmab141
  8. Mendoza N, Losa F, Palacios S. Strategy to improve the female fertility in the general gynecologist’s office: use of a nutritional supplement based on myo-inositol/D-chiro-inositol and antioxidants. Gynecol Endocrinol Off J Int Soc Gynecol Endocrinol. 2022;38(4):275-278. doi:10.1080/09513590.2021.2015759
  9. Hart RJ. Nutritional supplements and IVF: an evidence-based approach. Reprod Biomed Online. 2024;48(3). doi:10.1016/j.rbmo.2023.103770
  10. Viña I, Viña JR, Carranza M, Mariscal G. Efficacy of N-Acetylcysteine in Polycystic Ovary Syndrome: Systematic Review and Meta-Analysis. Nutrients. 2025;17(2):284. Published 2025 Jan 14. doi:10.3390/nu17020284
  11. XENOU M, GOUROUNTI K. Dietary Patterns and Polycystic Ovary Syndrome: a Systematic Review. Mædica. 2021;16(3):516-521. doi:10.26574/maedica.2020.16.3.516
  12. Wróblewski M, Wróblewska W, Sobiesiak M. The Role of Selected Elements in Oxidative Stress Protection: Key to Healthy Fertility and Reproduction. Int J Mol Sci. 2024;25(17):9409. doi:10.3390/ijms25179409
  13. Thornburgh S, Gaskins AJ. B vitamins, polycystic ovary syndrome, and fertility. Curr Opin Endocrinol Diabetes Obes. 2022;29(6):554-559. doi:10.1097/MED.0000000000000773
  14. Al-Bayyari N, Al-Domi H, Zayed F, Hailat R, Eaton A. Androgens and hirsutism score of overweight women with polycystic ovary syndrome improved after vitamin D treatment: A randomized placebo controlled clinical trial. Clin Nutr. 2021;40(3):870-878. doi:10.1016/j.clnu.2020.09.024
  15. Shin HJ, Na HS, Do SH. Magnesium and Pain. Nutrients. 2020;12(8):2184. Published 2020 Jul 23. doi:10.3390/nu12082184
  16. Morel V, Pickering ME, Goubayon J, Djobo M, Macian N, Pickering G. Magnesium for Pain Treatment in 2021? State of the Art. Nutrients. 2021;13(5):1397. Published 2021 Apr 21. doi:10.3390/nu13051397
  17. Parazzini F, Di Martino M, Pellegrino P. Magnesium in the gynecological practice: a literature review. Magnes Res. 2017;30(1):1-7. doi:10.1684/mrh.2017.0419
  18. Abdi F, Amjadi MA, Zaheri F, Rahnemaei FA. Role of vitamin D and calcium in the relief of primary dysmenorrhea: a systematic review. Obstet Gynecol Sci. 2021;64(1):13-26. doi:10.5468/ogs.20205
  19. Verkaik S, Kamperman AM, Westrhenen R van, Schulte PFJ. The treatment of premenstrual syndrome with preparations of Vitex agnus castus: a systematic review and meta-analysis. Am J Obstet Gynecol. 2017;217(2):150-166. doi:10.1016/j.ajog.2017.02.028
  20. Cerqueira RO, Frey BN, Leclerc E, Brietzke E. Vitex agnus castus for premenstrual syndrome and premenstrual dysphoric disorder: a systematic review. Arch Womens Ment Health. 2017;20(6):713-719. doi:10.1007/s00737-017-0791-0
  21. Sureja VP, Kheni DB, Dubey VP, et al. Efficacy and Tolerability Evaluation of a Nutraceutical Composition Containing Vitex agnus-castus Extract (EVX40™), Pyridoxine, and Magnesium in Premenstrual Syndrome: A Real-World, Interventional, Comparative Study. Cureus. 2023;15(8):e42832. Published 2023 Aug 2. doi:10.7759/cureus.42832
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  25. Lim EY, Lee SY, Shin HS, et al. The Effect of Lactobacillus acidophilus YT1 (MENOLACTO) on Improving Menopausal Symptoms: A Randomized, Double-Blinded, Placebo-Controlled Clinical Trial. J Clin Med. 2020;9(7):2173. doi:10.3390/jcm9072173
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